The Control Switcher will simply need to have Program Change and/or Control Change messages enabled to respond to the Nova System.
If you want the amp to only switch when you recall Nova System patches then you will likely only need to enable Program Changes in the Control Switcher.
If you want to have individual buttons to control the amp switching functions then you will want to enable Control Changes in the Control Switcher, and select the range of four Control Change numbers you want to use.
The Control Switcher defaults to using MIDI Channel 1.
There are two versions of the Control Switcher. Version 1 has Black Buttons and Version 2 has Red Buttons. Make sure you are using the manual for your version of the Control Switcher. You can look
here for the appropriate user manual.
Let us know if you get stuck!